Thanks for your report.
I have sent you an email with a debug version of WinSCP to the address you have used to register on this forum.

Problem occurs when starting WinSCP. Options are "Ok", "Help" and "Report". Clicking "Ok" closes the application.

WinSCP 5.17.10

Error message:
Invalid access to memory.

Stack trace:
(003C476E) System::Typinfo::IsStoredProp
(0008771F) ntdll.dll
(000740A1) ntdll.dll.KiUserExceptionDispatcher
(0039933B) System::Classes::TWriter::WriteCollection
(002B8431) Vcl::Comctrls::_17518
(002B84C0) Vcl::Comctrls::TListColumn::DoChange
(002B86A4) Vcl::Comctrls::TListColumn::SetWidth
(00008C36) TCustomScpExplorerForm::RestoreParams
(0004CBAA) TScpCommanderForm::TScpCommanderForm
(0023E962) Vcl::Forms::TApplication::CreateForm
(00E482CF) _SafeFormCreate
(00002658) wWinMain
(00F8814D) __wstartup
(00066C7C) ntdll.dll.RtlGetAppContainerNamedObjectPath
(00066C49) ntdll.dll.RtlGetAppContainerNamedObjectPath

(003C476E) System::Typinfo::IsStoredProp
(00F8A13A) C5296_0
(00F8C1A2) ____ExceptionHandler
(00F88F5C) __ExceptionHandler
(0008771F) ntdll.dll
(000740A1) ntdll.dll.KiUserExceptionDispatcher
(0039933B) System::Classes::TWriter::WriteCollection
(002B8431) Vcl::Comctrls::_17518
(002B84C0) Vcl::Comctrls::TListColumn::DoChange
(002B86A4) Vcl::Comctrls::TListColumn::SetWidth
(00008C36) TCustomScpExplorerForm::RestoreParams
(0004CBAA) TScpCommanderForm::TScpCommanderForm
(0023E962) Vcl::Forms::TApplication::CreateForm
(00E482CF) _SafeFormCreate
(00002658) wWinMain
(00F8814D) __wstartup
(00066C7C) ntdll.dll.RtlGetAppContainerNamedObjectPath
(00066C49) ntdll.dll.RtlGetAppContainerNamedObjectPath

I know how to reproduce the problem or the problem happens frequently enough. I wish to be contacted by the WinSCP team to help resolving the problem.