WinSCP installs a shell copy hook, but it runs not only in File Explorer but also in other processes that use the shell file copy API like SettingSyncHost.exe. Something happens in DragExt64 that it crashes and corrupts settings for the user.
09 000000c5`ce0fe500 00000000`63d21799 DragExt64!DllUnregisterServer+0x3e11f
0a 000000c5`ce0fe5f0 00000000`63d0f15e DragExt64!DllUnregisterServer+0x3e459
0b 000000c5`ce0fe620 00000000`63d11909 DragExt64!DllUnregisterServer+0x2be1e
0c 000000c5`ce0fe6c0 00000000`63d11585 DragExt64!DllUnregisterServer+0x2e5c9
0d 000000c5`ce0fe6f0 00000000`63ce3419 DragExt64!DllUnregisterServer+0x2e245
0e 000000c5`ce0fe720 00000000`63ce2660 DragExt64!DllUnregisterServer+0xd9
0f 000000c5`ce0fe750 00000000`63ce2a7d DragExt64+0x2660
10 000000c5`ce0fe790 00007ffd`44ce0c9b DragExt64+0x2a7d
00000000`63ce0000 00000000`63d52000 DragExt64 (export symbols) C:\Program Files (x86)\WinSCP\DragExt64.dll
Loaded symbol image file: C:\Program Files (x86)\WinSCP\DragExt64.dll
Image path: C:\Program Files (x86)\WinSCP\DragExt64.dll
Image name: DragExt64.dll
Browse all global symbols functions data
Timestamp: Mon Mar 9 08:07:21 2020 (5E665BA9)
CheckSum: 0007DCA5
ImageSize: 00072000
File version: 2.0.0.10278
Product version: 5.17.2.0
File flags: 0 (Mask 3F)
File OS: 4 Unknown Win32
File type: 2.0 Dll
File date: 00000000.00000000
Translations: 0409.04e4
Information from resource tables:
CompanyName: Martin Prikryl
ProductName: WinSCP
InternalName: dragext
OriginalFilename: dragext.dll
ProductVersion: 5.17.2.0
FileVersion: 2.0.0.10278
FileDescription: Drag&Drop shell extension for WinSCP (Win64)
LegalCopyright: (c) 2000-2020 Martin Prikryl